isrerg we;=¿jk úIîcj,g - tfrysj m‍%;sYla;s moaO;sh C%shdlrk whqre


Jul 13, 2020    Views: 9

isrerg we;=¿jk úIîcj,g - tfrysj m‍%;sYla;s moaO;sh C%shdlrk whqre

wmf.a isref¾ m‍%;sYla;sh <udúfhka j¾Okh ùu mgkaf.k ;reKúh jk úg Wmßu uÜgug m;ajkjd' bkamiq C%uC%ufhka jhig hk úg m‍%;sYla;slrK moaO;sfha C%shdldÍ;ajh ÿ¾j,ùug m;afjkjd' tfiau Èhjeähdj" jl=.vq frda. wdÈh ksid;a tÉ'whs'ù' jeks ffjri frda. ksid;a we÷u jeks ksOka.; frda. ksid;a isref¾ m‍%;sYla;sh wvqfjkjd

fldúÙ 19 ffjri frda.h f,dj mqrd jix.;hla f,i me;srhkakg mgka .ekSu;a iu. wmg h<s wm YÍrfha m‍%;sYla;sh .ek isysm;a lr.kakg isÿj we;' isref¾ m‍%;sYla;sh ÿ¾j, mqoa.,hkg fuu frda.h je<£fï bvlv jeä nj ffjoHjre i|yka lsÍu;a iu. fndfyda fokd ;u isref¾ m‍%;sYla;sh jeälr .ekSu flfrys fjkodg jvd Wkkaÿjla olajkakg mgkaf.k we;' ta i|yd úúO wdydrmdk .ks;s' T!IO j¾. mdkh lr;s' tla whqrlska fuh fyd| mqreoaols' fujeks miqìul wm isref¾ C%shd;auljk m‍%;sYla;slrK moaO;sh ms<sn|j;a hï wjfndaOhla ,nd.ekSu jeo.;ah'

ffjoH ;=uks wm isref¾ wmg Wreuj we;s m‍%;sYla;slrK moaO;sh C%shdlrkafka flfiao@

wm isrerg ndysßka we;=¿jk frda.j,g iy úIîcj,g tfrysj C%shdlrk wdrlaIl moaO;shla we;' thg m‍%;sYla;slrK moaO;sh lshd y÷kajkq ,nkjd' th C%shd;aul jk wdldrh fldgia follg fnod fjkalr oelaúh yelshs'

lsishï úIîchlg úfYaI fkdù fmdÿfõ isrerg ndysßka we;=,ajk úI îcj,g tfrysj m‍%;sYla;slrK moaO;sh C%shd lsÍu ^Innate immune system& iy m‍%;sfoay cklj,g ^Antigen& úreoaOj Bgu úfYaIs; jQ m‍%;sYla;shla YÍrh ;=< we;sùu ^specific immunity& f,iska wmf.a m‍%;sYla;s moaO;sh wdldr follg C%shdlrkjd'

ndysßka we;=,ajk úIîcj,g tfrysj m‍%;sYla;slrK moaO;sh C%shdlsÍu^Innate immune system&

wmf.a YÍrhg ndysßka fkdfhl=;a úI îc we;=¿fõ' tu úI îcj,g tfrysj m‍%;sYla;slrK moaO;sh C%shd;auljk whqre WodyrK lsysmhlska úuid n,uq' tys§ wmf.a isref¾ úYd,;u bkao%shjk iu C%shdlrk wdldrh fufiah' iu wmg msgia;r wdjrKhla f,i C%shdlrhs' tksid iu ;=<ska isrerg we;=¿ úh yels úIîc úkdY lsÍug iu we;=<; úfYaI Nla‍IdKq ^Macrophage& mj;skjd' tu.ska isrerg ndysßka we;=¿jk nelaàßhd" ffjri wdÈh ldouñka ^NlaIKh lrñka& tajd úkdY lrkjd' Bg wu;rj iu úh<Sug ,laj leühEug bv fkd§ kSfrda.Sj mj;ajd .ekSug iafkay Y‍%dùh o%jHhka ksmojd Y‍%djh lrkjd' fuf,i ndysßka isrerg we;=,ajk úIîcj,g tfrysj fmdÿfõ C%shdlrk ;j;a wjia:djla f,i Yaf,aIau, mgl oelaúh yelshs' Yaf,aIau, mg,j,ska uqLh" iajik moaO;sh" nvje,a wdÈh wdia;rkhg ,lalrñka úI îcj,ska wdrlaId lrkjd' tfiau Yaf,aIau, o%jH Y‍%djh lrñka tajdfha we;s úúO ridhk o%jH u.ska úIîc úkdY lrkq ,nkjd' Bg wu;rj iajik moaO;sfha kdifha isg fmky¿ olajd my<g mlaIau keue;s b;d l=vd flia jeks ;ka;= j¾.hla mj;skjd' tajd fmky¿j, isg by<g uqyqÿ /q,a,la yd iudkj p,kh fjñka .uka lrkjd' fuu mlaIau u.ska iajik moaO;shg we;=¿jk úIîc fmky¿ olajd .uka lsÍug bv fkd§ msg;g /qf.k tkjd' tfia /qf.k tk úIîc W.=r olajd meñKs miq leiaila we;s lr th uqLfhka msg lrkjd' tfiau reêrfhyso úIîc kik NlaIdkq ;sfnkjd'

kshqfg%d*s,¾" ^Neutrophil& fNafid*s,¾" ^Basophil& hqiqfkd*s,¾ ^Eosinophil& wd§ fuu NlaIdKq u.ska reêrhg we;=¿jk úIîc úkdY lrkjd' mgl ;r,fha isák uyd NlaIdkq u.ska o isrerg we;=¿jk úIîc ld ouñka úkdY lrkjd' fuu m‍%;sfoayhka lsisÿ úI îchlg úfYaI fkdù isrerg we;=¿jk ish¨u wd.ka;=l o%jHj,g tfrysj C%shd lrkjd'

&m‍%;sfoay cklj,g úreoaOj Bgu úfYaIs;jQ m‍%;sYla;shla YÍrh ;=< we;sùu ^specific immunity&

hï úIîchla fyda wd.ka;=l o%jHhla wm m‍%;sYla;s moaO;sh u.ska y÷kdf.k m‍%;spdr olajk ridhksl ldKav m‍%;sfoay ckl ^Antigen& f,i y÷kajkjd' iEu m‍%;sfoay cklhlgu úreoaOj Bgu úfYaIs; jQ m‍%;sYla;shla YÍrh ;=<ska we;sfjkjd' fuu úfYaIs; m‍%;sfoay ^specific immunity& C%shdlrk wdldr fufiah' isrerg we;=¿jk wd.ka;=l úI îchg tfrysj C%shdlrk ffi, j¾. /qila jid moaO;sfha mj;skjd' tu ffi, w;ßka T keue;s ffi,j,g wd.ka;=l úI îcfhys we;s fm%daàk NlaIdkq u.ska ms,s.kajkjd' tfia ms,s.kajd tu úIîcfhys we;s fm%daàkj,g tfrysj úfYaIs; igkla C%sshd;aul lrkjd' fuf,i we;slrk igfka§ isÿlrk C%shd ud,djka /ila u.ska ;j;a ffi, rdYshla iC%ShNdjhg m;afjkjd' túg fuu úIîcfhys we;s fm%daàkj,g tfrysj m‍%;sfoay ksmojk f,ig jid moaO;sfha we;s B ffi,j,g ix{djla ksl=;a lrkjd' fuu.ska tu wd.ka;=l úIîch úkdY lrkjd' m‍%;sfoay j¾.;a folla ;sfnkjd' laIKsl m‍%;spdr olajk ^IGM& iy §¾> ld,Sk m‍%;spdr olajk ^IGG& m‍%;sfoay f,iska tajd y÷kajkjd' m‍%;sfoay iE§u u.ska m‍%;spdr olajk ffi,j,g u;l ;nd;ekSfï yelshdjla mj;skjd'^Memory T cells& tu ffi, u.ska isrerg kej; jrla fujeks wd.ka;=l úIîc meñKshfyd;a Bg tfrysj igka lrkjd'

óg wu;rj we;eï wjia:dj,§ isrer ;=< úIîcj,g tfrysj isÿjk igfka§ ksmojk iuyr ridhk o%jH ^Interleukin $gamma interferon& úIîcj,g tfrysj igka lsÍug wjYH m‍%;spdrhg jvd jeä m‍%;spdrhla olajkjd' tys§ úIîcj,g tfrysj igka lsÍug wjYH m‍%udKhg jvd ridhk o%jH ksmoùu ksid úIîcj,g tfrysj igka lrkjdg wu;rj isref¾ we;s ffi,j,g;a ydks isÿfjkjd' fuh md,khlska f;drj m‍%;sYla;sh ksmoùuls' tys§ frda.shd wk;=rg ,lajkafka úIîc ksid fkdj fuu md,khlska f;drj ksmojk ridkh o%jH ksid isref¾ ;sfnk wfkla ffi, úkdYùu ksidh' ukaoh;a bka isrer ;=< yg.kakd wêl m‍%‍%odyh ksid iajik moaO;sh" reêr moaO;sh iy jl=.vq wdÈh ydkshg ,lafjkjd' fldfrdakd ffjri frda. ;;a;ajfha§ isÿjkafka;a fujeks wêl m‍%;spdrhla oelaùu ksid fmky¿ iy wfkl=;a bkao%shkays ffi, úkdYùuh' tfiau fvx.= frda.fha§ fvx.= rla;md;h we;sjkafka;a fuf,i úIîcj,g tfrysj jeä m‍%;spdr oelaùu ksidh' tys§ we;sjk wêl m‍%;spdrh ksid reêrjdyskSj,g ydks isÿùfuka rla;md;h we;slrkjd' tksid fuf,i md,khlska f;drj isrer ;=< m‍%;sYla;sh we;sùu;a ydkslrhs'

ffjoH ;=uks m‍%;sYla;s moaO;sh ÿ¾j, jk wjia:d ;sfnkjdo@

wmf.a isref¾ m‍%;sYla;sh <udúfhka j¾Okh ùu mgkaf.k ;reKúh jk úg Wmßu uÜgug m;ajkjd' bkamiq C%uC%ufhka jhig hk úg m‍%;sYla;slrK moaO;sfha C%shdldÍ;ajh ÿ¾j,ùug m;afjkjd' tfiau Èhjeähdj" jl=.vq frda. wdÈh ksid;a tÉ'whs'ù' jeks ffjri frda. ksid;a we÷u jeks ksOka.; frda. ksid;a isref¾ m‍%;sYla;sh wvqfjkjd' Bg wu;rj fkdfhl=;a cdkuh wvqmdvq fya;=fjka Wm;skau m‍%;sYla;sh wvq wh isákjd' we;eï frda. i|yd ,ndfok T!IO ksid;a m‍%;sYla;sh ÿ¾j, fjkjd' WodyrKhla f,i we÷ug ,ndfok fm%ä‍%isf,daka ^Prednisolone& keue;s T!IO ksid m‍%;sYla;sh wvqfjkjd' jl=.vq noaOlsÍu" wlaud noaOlsÍu jeks bkao%sh noaOlsÍï j,ska miq noaO l< bkao%shg tfrysj isreßka we;sjk m‍%;sfrdaOh wju lsÍu i|yd isref¾ m‍%;sYla;sh wvqlsÍug mshjr .ekSu ksid;a isref¾ m‍%;sYla;sh wvqfjkjd' iuyr mqoa.,hkaf.a we;eï wjia:dj,§ Tjqkaf.au isref¾ mglj,g úreoaOj m‍%;sYla;s moaO;sh C%shd;aul fjkjd'

fuys§ isref¾ fldgia m‍%;sYla;s moaO;sh u.ska wd.ka;=l m‍%;sfoay ckl f,i i,ld C%shdlrkjd' ^Auto immune disoder& túg tu m‍%;súreoaO m‍%;sYla;sh ksid ffi, yd mgl wdÈhg ydks isÿfjkjd' fuf,i m‍%;súreoaO m‍%;sYla;sh ksid ikaêj, mgl ydkshg ,laùu ksid we;sjk frda.hla f,i rEufgdhsÙ wd;rhsàia frda.h oelaúh yelshs' tfiau isrerg ksis fmdaIKh fkd,eîu ksid;a m‍%;sYla;sh ÿ¾j, ùug m;afjkjd' tys§ úgñka î" iS" ü iy fm%daàka wdÈfhys we;sjk W!K;d isref¾ m‍%;sYla;sh wvqùug b;d oeäj n,mdkjd' óg wu;rj ;j fkdfhla frda. iy fya;= /qila ksid;a isref¾ m‍%;sYla;sh ÿ¾j,ùu isÿfjkjd'


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